Pharma

Preparation of solutions for the mass extrusion

Our solutions for the production of wet granulation solutions have the following key benefits:

  • a special in-line dosing system
  • flexible connections of reactors and mixing vessels to the pipe systems or other reactor vessels
  • use of organic solvents or only water
  • standard volumes (2, 5, 10, 20, 50, 100, 170, 250 l) or custom-tailored
  • mobile containers of more than 20 l and containers adapted for manual transport
  • Brinox standard or magnetic stirrers installed on the bottom of the container and other custom-tailored mixers such as dissolvers and turbine mixers
  • possible connection to central CIP, drying in place,
  • if heating or cooling is requested, the unit for preparing solutions can be connected to Brinox technological tempering

Our solutions comply with customer requirements and provide flexible production of granulation solutions. The same transport containers can be used for the preparation of granulation solutions and coating suspensions.

Preparation of mass for extrusion

Our solutions for the pellet line production provide:

  • standard useful volumes from 5 l to 2000 l or custom-tailored
  • use of organic solvents or only water
  • use of a top shear mixer
  • a special system for optimum utilisation by means of sleeve cooling after completed mass preparation
  • the use of a high-shear dryer for drying substances prior to mass preparation
  • designated systems for heating, cooling or connection to the central system
  • connection to designated or central CIP and drying in place
Preparation of coating suspensions

The use of dissolvers, various types of homogenisers and systems for the separate preparation of colour additives in accordance with technological processes of users is one of our advantages.

We provide:

  • use of organic solvents or only water
  • standard volumes (2, 5, 10, 20, 50, 100, 170, 250 l) or custom-tailored, adapted also for heating/cooling with hot water
  • containers of more than 20 l, mobile, smaller ones adapted for manual transport
  • installation of mixers in accordance with customer technology
  • connection to central CIP, DIP
  • if heating or cooling is requested, the unit for preparing film-coating solutions can be connected to Brinox technological tempering equipment

Coating suspensions and preparation solutions for the extrusion mass can be prepared in the same transport vessels.

References
Teva
CSL Behring
Sotex
Leo Pharma
Pharmathen
Aerie Pharmaceuticals
Dottikon
GlaxoSmithKline
Alcon
Novartis
Takeda
Fresenius Kabi
Merck
Galderma
Pfizer
Lek
Johnson & Johnson
Bionorica
Krka
Lonza
Sandoz
Zoetis
Alkermes
Capsugel
Pharmstandard
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