Pharma

• a special in-line dosing system,
• flexible connections of reactor and mixing vessels to the pipe systems or other reactor vessels,
• use of organic solvents or only water,
• mobile vessels, 
• integrated stirrers depending on the client’s requirements, 
• possible connection to a central CIP and DIP module,
• possible connection to a cooling/heating unit,
• mechanical finish of all contact and sealing surfaces, sealing without blind spots,
• the use of retractable washing heads for cleaning in place,
• the automated dosing of ingredients and control weighing.

Our solutions comply with customer requirements and provide flexible production.

Our added value is the professional special chemical cleaning procedure that includes the removal of all impurities and passivation of stainless surfaces after welding and grinding.

The inlet and outlet holes are made in line with the client’s requirements.

Our competitive advantage is the adaptation to the client’s existing systems already owned by potential partners, and help with the standardisation of MHS systems.
 

Properties: 

• Automated using a SCADA system,
• long service life,
• SMEPAC certificate,
• built in line with GMP requirements,
• allow for safe operation and management (OEB 3 certificate),
• easy to maintain and clean, with a lower cleaning medium consumption,
• active cooling – after cleaning they are ready for use in 30 minutes (optional),
• deaeration valve preventing vacuum (optional),
• the innovative Brinox washing nozzle ensures efficient washing and drying.

The drive can be manual, pneumatic or a combination of both. We build different solutions as requested by the clients.

We produce two types of valves (DN 100, 150, 200, 250, 300):

• with soft flaps for MHS systems for tablets, capsules
• with stainless flaps for MHS system for granulates, powders

The most used conical valve is the DN 400 mm, used especially in cases of poorly flowing powder materials.

The conical valve is installed in the IBC.

At the installation site the receiving unit is connected to the process device or receiving container.

The system of conical valves produced by Brinox is used for:

• multilevel gravity transfer of powder materials, tablets and capsules,
• single-level gravity system.
   

The special double-flanged construction ensures that no mixing of the heating or cooling medium with the pharmaceutical liquid can occur; this prevents contaminations.

• batch sizes from 10 to 600 L, 
• the execution of all three operations with a single system, 
• a homogeneous distribution of particles, 
• influencing the coating quality, 
• a shorter process time, 
• fully automated operation supervision functions, 
• automated washing of the system (CIP),
• explosion safety (due to the innovative seal the system can withstand pressures up to 12 bar),
• leakage-proof operation during the process decreases the operator’s exposure.

The system is made from AISI316L stainless steel and equipped with standard measuring instruments and other automation components.  
 

We assure:

• the safe addition of additives to ensure the prescribed OEB and explosion safety (with Brinox MHS systems),
• IBCs from our own production that allow us to adapt to the client’s requirements and introduce the required blending,
• the production of mixers adapted to the client's requirements

• to align the vessel body or connecting pipe with the retractable head front,
• a very good distribution of the jet to the rotating manifold,
• good wetting results (wetting angle 220–180°),
• the retractable head is self-cleaning and used in pairs,
• retractable heads are used also to distribute hot compressed air or nitrogen for drying.
   

Brinox provides an efficient system for precisely dosing detergents to washing systems in accordance with recipes, to monitor consumption by working order or cost centres, and easy logistics.

The detergent storage and distribution system is built in such a way as to provide the distribution installations for each CIP module or washing system.

The required dosing uses separate volume dosing pumps.
Storage systems can use standard containers or the detergents can be stored in separate vessels.