Filtration and Storage of Injection Solutions before Filling

Characteristics of the Brinox process system:

• In-line sterilization of the pre-filter and sterile filter with clean saturated steam (SIP)
• In-line automatic rinsing of the pre-filter and sterile filter with water for injections
• The solution passes steadily through the filters and prevents early clogging of the filter inserts
• The storage tanks have the same volume as the main mixer
• The filter unit (including the filtration housing) is automatically purged
• In-line integrity test of the sterile solution filter, or the filter for sterile filtering of inert gas

Additional Options:

• Drying of the entire filtration unit with sterile filtered inert gas (DIP).
• An additional filter for the sterile filtering of inert gas can be incorporated into the process of a SIP-filtration unit to allow for simultaneous sterilization and drying with a sterile solution filter.